Analysis of Bacterial Genomes Begins to Unravel Complex Story of Metabolic Evolution As any biochemist knows, genetic change is actually chemical change, and so it follows that if you would like to see how evolution happens really, you need to see how it affects biochemistry click here read more . A genetic analysis looking for the evolutionary history of nitrogenase, the essential enzyme system that helps life use atmospheric nitrogen, has shown some interesting evolutionary romantic relationships between your key metabolic processes of bacteria, and revealed some mystical new chemical substance pathways that are not yet understood. In a paper published in today’s problem of the journal Molecular Biology and Evolution , Arizona State University biochemists Jason Raymond, Christopher Staples and Robert Blankenship and Rice University’s Janet Siefert do an analysis of the genomes of a big group of bacteria and archaea, comparing specifically similar genes that make the protein nitrogenase.