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In immersion injuries, the bloodstream and nerves vessels are broken after contact with cold, wet circumstances at or above freezing temps. Pernio is caused by exposure to chilly for a long period of time without freezing or by very wet conditions. Raynaud’s phenomenon can be an abnormal narrowing of the blood vessels that constrict with cooling of the fingers or toes. Cryoglobulins are proteins, which are usually dissolved in the bloodstream, that become solids or gels when frosty. Cryoglobulinemia is the condition associated with cryoglobulins in the bloodstream, whereby cold publicity leads to bluish discoloration of the fingertips or toes. The formation of hives in response to chilly exposure of your skin is named cold urticaria..