Aspirin may protect against colon cancer in some Aspirin may dramatically reduce risk for colon cancer, according to a new study pharmacy journal . But, the effect seems to end up being limited to individuals who lack specific genetic mutations tied to tumor risk. The study that viewed nearly 130,000 people adds even more evidence to the cheap, chalky white pill’s disease-fighting properties and its own limitations. ‘This finding further works with the usage of aspirin for the prevention of colorectal cancer, but adds an additional nuance, in that not all colon cancers behave the same way,’ study author Dr. Andrew Chan, a gastroenterologist from the Massachusetts General Medical center in Boston, told Medscape.